Overview
Andreessen Horowitz is a venture capital firm investing across technology sectors with a dedicated AI practice [1]. The firm lists AI as a dedicated focus area on its website [3]. In Q2 2026, Andreessen Horowitz was ranked among the 10 most active investors in NYC startups, completing 7 deals during that period with a focus on AI-native financial infrastructure [2].
Org chart
14 alumniInvestments
EliseAI
Agentic AI automating patient and resident communications for healthcare and housing organizations
OpenRouter
Company founded in 2023 by Alex Atallah and Louis Vichy, operating a routing platform that connects AI applications to language models and cloud inference providers.
Tennr
NYC healthcare AI company founded in 2021 by Trey Holterman, Diego Baugh and Tyler Johnson, offering an automation platform for processing medical documents and referrals.
Raspberry AI
New York-based generative AI platform for fashion design, letting apparel teams create and iterate on designs with AI.
Pearl Health
New York company using data and risk analytics to help primary care providers succeed in value-based care.
Pomelo Care
NYC healthcare technology company founded in 2021 by Marta Bralic, delivering evidence-based virtual maternity and pediatric care for women and children.
Vibranium Labs
NYC company cofounded by Sang Lee and Tim Hwang, whose Vibe AI agentic platform proactively monitors, triages and resolves IT incidents before they reach customers, integrating with PagerDuty, Jira and Datadog.
Adaptive Security
Adaptive Security is a security training and phishing simulation platform protecting businesses from AI-driven and emerging threats. Adaptive Security was founded by Andrew Jones and Brian Long in 2022 and is backed by investors that include Abstract, Andreessen Horowitz, Bain Capital Ventures, Capital One Ventures, Citi Ventures, nVentures, and OpenAI Startup Fund.
Protege
New York City-based AI data platform enabling secure exchange of proprietary real-world datasets for AI pre-training, fine-tuning and evaluation.
Slingshot AI
New York company building Ash, a foundation-model-based AI product for mental health support.
Prepared
New York City-based company offering an AI-powered platform that transcribes, translates, and triages 911 calls to enhance emergency response operations.
Graphite
NYC company founded by Merrill Lutsky, Greg Foster and Tomas Reimers, offering an open-source CLI and AI code review dashboard for engineering teams.
Moment
NYC company founded by Dylan Parker, Dean Hathout and Ammer Soliman, building a fixed-income operating system that automates trading and portfolio management workflows.
Deeptune
A developer of high-fidelity reinforcement learning environments, or training gyms, that simulate real-world digital workflows so AI agents can learn to perform complex enterprise tasks
Prosper
Prosper builds AI phone agents for healthcare providers.
Ornn AI
A financial infrastructure company that provides compute exchange and financing products for AI infrastructure buildout
Probook
An AI operating system for home services businesses that automates dispatch, customer communications, and scheduling workflows
Pillar
A financial risk management platform that automates commodity and currency hedging for small and medium-sized businesses
In the news
- The Weekly Notable Startup Funding Report: 9/28/26The notable startup funding rounds for the week ending 9/26/26 featuring funding details for Hydrosat, Numeral, Firecral, and nineteen other deals representing $2.5B in new funding that you need to know about.
AlleyWatch · Sep 27, 2026
- Adaptive Raises $30M to Expand Its AI Workforce Across the $2T Construction MarketMatt Calvano's investors describe Adaptive as one of the most important tools their portfolio companies keep in their stack, a rare compliment in construction software. The company just closed a $30M Series B, bringing total funding to $57M, to keep building out the AI agents that do construction accounting work instead of just tracking it. More than 750 construction companies already run their bo
- The Weekly Notable Startup Funding Report: 9/21/26The notable startup funding rounds for the week ending 9/12/26 featuring funding details for Comp AI, Factory, MIND, and twenty-eight other deals representing $2.8B in new funding that you need to know about.
- Vals, backed by Andreessen Horowitz, is looking to become the gold standard for AI benchmarkingVals AI is hoping to make AI benchmarking a more neutral and trustworthy resource in a world increasingly inundated by AI models.
TechCrunch Startups · Sep 19, 2026
- The 15 Largest US Funding Rounds of August 2026US startups secured massive funding rounds in September 2026, with the largest deal topping $1.1B. From autonomous trucking and nuclear energy to AI chips and live commerce, this month's biggest raises span 25 companies across industries reshaping the future. See which startups made the list.
- The AlleyWatch Startup Daily Funding Report: 9/17/2026The latest venture capital, seed, pre-seed, and angel deals for NYC startups for 9/17/2026 featuring funding details for Adaptive, Polyphron, and much more.
- The August 2026 US Venture Capital Funding Report$18.1B. 333 deals. August was supposed to be the slow month. Instead, the US venture market delivered one of the most capital-intensive Augusts on record — a 123% year-over-year surge driven by River AI's $1.1B Series A, Base Power's $1.0B Series D, and a wave of defense, clean energy, and AI infrastructure rounds that have no precedent in the summer data.
- The AlleyWatch Startup Daily Funding Report: 9/14/2026The latest venture capital, seed, pre-seed, and angel deals for NYC startups for 9/14/2026 featuring funding details for Highstock, UrgentIQ, and much more.
Alumni 1 went on to found or lead
Jeffrey Low, MDPartner, Bio Fund (now Bio + Health)→Partner at Averin
NYC presence
- Ranked among the 10 most active investors in NYC startups in Q2 2026 with 7 deals, focused on AI-native financial infrastructure[2]
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