TwentyTwo

AI infrastructure for biosecurity[1][2][8][15]

Overview

TwentyTwo is an AI infrastructure company focused on biosecurity [2]. Based in New York City [4], the company was accepted into Y Combinator's Summer 2025 batch [5] and remains active [6]. The company operates with a team of three people [7]. According to its Y Combinator profile, TwentyTwo addresses the dual-use implications of artificial intelligence in biology: while AI is accelerating the development of life-saving drugs and therapies, it simultaneously enables bad actors to create pandemic threats [3]. The company describes its mission as building defensive infrastructure to prevent the next pandemic [3].

AI is making biology easy to engineer. Life-saving drugs and therapies are accelerating, but so is the ability for bad actors to create a pandemic. TwentyTwo is working on the defensive stack to prevent the next pandemic. [3] [9]

New York City, NY, USA [4]

New York City [11]

2025 [12]

Located in New York City, NY [16]

Y Combinator's directory lists the company location as New York City, NY, USA. [18]

Growth & traction

count: 3 [7]

3 [13]

Y Combinator lists a team size of 3. [20]

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